GW 3965 (hydrochloride) from Cayman Chemical

Product Specs
ItemGW 3965 (hydrochloride)
CompanyCayman Chemical
Price Pricing Info Supplier Page View Company Product Page
Catalog Number10054
FormatA crystalline solid
Research AreaCarbohydrate Metabolism, Cardiovascular Diseases, Cardiovascular System, Endocrinology & Metabolism, FXRs & LXRs, Hormones & Receptors, Hypertension, Immunology & Inflammation
Molecular Weight618.5
Quantity10 mg
Purity≥98%

Add to Compare List

Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Systematic elucidation of genetic mechanisms underlying cholesterol uptakeCell GenomicsMay 10, 2023Marisa C. Hamilton, James D. Fife, Ersin Akinci, Tian Yu, Benyapa Khowpinitchai, Minsun Cha, Sammy Barkal, Thi Tun Thi, Grace H.T. Yeo, Juan Pablo Ramos Barroso, et al.Pyripyropene A,Cayman,Cat#11896 Fatostatin,Cayman,Cat#13562 KX2-391,Cayman,Cat#21429 MHY1485,Cayman,Cat#18008 GW3965,Cayman,Cat#10054 Rocaglamide A,MedChemExpress,Cat#HY-19356 Rho Activator II,Cytoskeleton.com,Cat#CN03-A Tempol,Cayman,Cat#27051 Simvastatin,Cayman,Cat#10010344 Puromycin Dihydrochloride

(2) Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formationCell chemical biologyJune 17, 2021Hubler Z, Friedrich RM, Sax JL, Allimuthu D, Gao F, Rivera-León AM, Pleshinger MJ, Bederman I, Adams DJ.Chemicals,Cat#10009931 25-hydroxycholesterol,Cayman Chemicals,Cat#11097 T0901317,Cayman Chemicals,Cat#71810 GW 3965,Cayman Chemicals,Cat#10054 WAY252623,Cayman Chemicals,Cat# 21117 SR9238,Cayman Chemicals,Cat# 18771 Fenhexamid,Sigma Aldrich,Cat#

(3) SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1The Journal of biological chemistryJanuary 1, 2021Wang JQ, Lin ZC, Li LL, Zhang SF, Li WH, Liu W, Song BL, Luo J.β-mercaptoethanol (#M3148) were from Sigma-Aldrich. DiI-LDL was from Yeasen (#20614ES76). GW3965 (#10054) was from Cayman. Lipofectamine RNAiMAX (#13778150) was from ThermoFisher. SUMO1-AMC (#UL-704), ubiquitin-AFC

(4) LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human MonocytesFrontiers in immunologyJanuary 1, 2020Sohrabi Y, Sonntag GVH, Braun LC, Lagache SMM, Liebmann M, Klotz L, Godfrey R, Kahles F, Waltenberger J, Findeisen HM.(Greiner Bio-OneTM) with 2 μg/ml BCG, 2 μM T0901317 (T1317) (Cayman, #71810), 10 μM GW3965 (Cayman, #10054), 5 μM GSK2033 (Cayman, #25443), 500 μM acetyl-CoA (Cayman, # 16160) or 10 ng/ml IL-1β (Peprotech, #200-01A)

(5) Low‑density lipoprotein receptor expression is involved in the beneficial effect of photodynamic therapy using talaporfin sodium on gastric cancer cellsOncology LettersFebruary 1, 2019Tsutomu Kanda et al.antibiotics. The cells were cultured in a humidified incubator with 5% CO2 at 37°C. Reagents TS, GW3965 (10054) and simvastatin (196–17801) were purchased from Meiji Seika Pharma Co., Ltd. (Tokyo, Japan), Cayman Chemical

(6) Chronic Activation of Liver X Receptor Sensitizes Mice to High Cholesterol Diet–Induced Gut ToxicityMolecular PharmacologyOctober 1, 2018Wojciech G. Garbacz, Hirdesh Uppal, Jiong Yan, Meishu Xu, Songrong Ren, Donna B. Stolz, Min Huang, Wen Xieof T0901317 (20 mg/kg) (cat. no. 71810; Cayman Chemical, Ann Arbor, MI), GW3965 (20 mg/kg) (cat. no. 10054, Cayman), or ezetimibe (10 mg/kg) (cat. no. SML1629 from Sigma-Aldrich, St. Louis, MO) were given. Ezetimibe

(7) The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X ReceptorEBioMedicineAugust 1, 2017Hammer SS, Beli E, Kady N, Wang Q, Wood K, Lydic TA, Malek G, Saban DR, Wang XX, Hazra S, et al.with LXR activator, DMHCA (0.1 μM/1 μM) (700125P; Avanti Polar Lipids; Alabaster, AL), GW3965 (10 μM) (10054; Cayman Chemical; Ann Arbor, MI) or SIRT1 activator SRT1720 (1 μg) (S1129; Sellechem; Houston, TX) for

(8) LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 geneOncotargetJanuary 17, 2017Susanna Ambrosio, Stefano Amente, Carmen D. Saccà, Mario Capasso, Raffaele A. Calogero, Luigi Lania, Barbara Majellowere treated with TCP (1mM, Enzo Life Sciences), SP2509 (0,3/0,5/1 μM, Cayman Chemical Company) or 10054-F4 (75 μM, Sigma) for 24 or 48 hrs. To induce differentiation in SK-N-BE (2) cells were exposed to 10

Be the First to Write a Review!

GW 3965 (hydrochloride) from Cayman Chemical

Description

Cayman Chemical

Citations (8)

Reviews

GW 3965 (hydrochloride) from Cayman Chemical

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map